Intraoperative blood loss may be associated with myocardial injury after non-cardiac surgery

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The aetiology of myocardial injury after non-cardiac surgery

Recognition of myocardial injury after non-cardiac surgery is difficult, since strong analgesics (e.g. opioids) can mask anginal symptoms, and ECG abnormalities are subtle or transient. Thorough knowledge of the pathophysiological mechanisms is therefore essential. These mechanisms can be subdivided into four groups: type I myocardial infraction (MI), type II MI, non-ischaemic cardiac pathology...

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Association between Intraoperative Hypotension and Myocardial Injury after Vascular Surgery.

BACKGROUND Postoperative myocardial injury occurs frequently after noncardiac surgery and is strongly associated with mortality. Intraoperative hypotension (IOH) is hypothesized to be a possible cause. The aim of this study was to determine the association between IOH and postoperative myocardial injury. METHODS This cohort study included 890 consecutive patients aged 60 yr or older undergoin...

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Low-Dose Sevoflurane May Reduce Blood Loss and Need for Blood Products After Cardiac Surgery

Patients undergoing cardiac surgery often experience abnormal bleeding, due primarily to cardiopulmonary bypass (CPB)-induced activation of platelets. Sevoflurane may inhibit platelet activation, raising the possibility that administering it during CPB may reduce blood loss.Patients between 18 and 65 years old who were scheduled for cardiac surgery under CPB at our hospital were prospectively e...

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A Higher Meal Frequency May be Associated with Diminished Weight Loss after Bariatric Surgery

OBJECTIVE This study aimed to investigate the relationship between meal frequency, the occurrence of vomiting and weight loss among patients submitted to Roux-en-Y gastric bypass up to 9 months after surgery. METHODS Female patients (n = 80) were followed at 3-month intervals for 9 months. Weight, BMI, 24-hour dietary recall, drug consumption and vomiting episodes were recorded and compared w...

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Association between intraoperative heart rate and postoperative myocardial injury in patients following non-cardiac surgery

Introduction Approximately 10% patients who undergo non-cardiac surgery show biochemical evidence of myocardial injury, which is associated with cardiac complications and death [1]. The aetiology and mechanisms of perioperative myocardial injury are incompletely understood. Observational studies have described associations between perioperative tachycardia and postoperative cardiac complication...

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ژورنال

عنوان ژورنال: PLOS ONE

سال: 2021

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0241114